How can I get an emergency dose of my antidepressant when my prescription has run out?. As you do not seem to be a danger to yourself or others, or completely incapacitated, you oughtn’t be kept against your will. However, there is still the risk of being misdiagnosed or misdirected, so keep in mind the danger involved. Like with all these options, bring your pill bottle and doctor. You need to ask the prescription service to fill it before you run out they need to know that you cannot stop cold turkey from taking this it can make you very sick they should know that Votes: +3 DO Hello, I am about to run out of my prescription for 150mg of Effexor. I have a new prescription, but I lost the paper that the doctor had given me. But you do have to be weened off this medication for sure. Make a dr. appointment as soon as you can. Even being out for a day is tough. Make a dr. appointment as soon as you can. Even being out for a day is tough. For example, Effexor is for social anxiety and zoloft is for generalized depression. So, the Effexor might not be enough to cover why you have the depression. Whatever you do, try to get your Zoloft refilled as soon as possible. If you stop immediately, the withdrawal symptoms can be awful. God bless you. I take the sane meds , 300 mg daily- after thd first few days I don't feel anything because Effexor is the type of medication that leaves your body right away- if you use myhealthevet you can order your meds well in advance of not having to wait till you run out If you find that you have unintentionally run out of Effexor, call your pharmacy and inquire as to whether you have any refills left. If you do, all you may need to do is go over and pick up your new pills. I can't afford to refill out of pocket, but I do have 75 mg of Effexor XR from an older prescription. Dr. Z : Actually I am a Clinical Psychologist with a post-graduate degree in Psychopharmacology, which gives me privileges to prescribe medications if I choose.